Publicaciones

El año 2017, el CREAS cumple 10 años, constituido sobre la base de dos grandes proyectos, de 5 años de duración cada uno: Proyecto de iniciación, con el cual logramos la creación de un Centro Regional con personalidad jurídica propia, metas claras y gobernanza definida y el Proyecto de continuidad, con el cual el CREAS se posiciona como una Institución dedicada a la investigación, la innovación y la transferencia tecnológica de alimentos más saludables. Con orgullo mencionamos que el
resultado de este último proyecto tuvo una óptima evaluación de la comisión de pares externos asignada por CONICYT.

Memorias

Memoria CREAS 2017

Memoria CREAS 2016

Memoria CREAS 2015

Publicaciones ISI

Publicaciones del grupo de investigación en los últimos 5 años en revistas de corriente principal (ISI)

Field responses of potato to increased temperature during tuber bulking: Projection for climate change scenarios, at high-yield environments of Southern Chile.
Agricultural and Forest Meteorology, 239, 192-201.
Investigadores: X. Carolina Lizana, Andrea Avila, Alejandro Tolaba y Juan Pablo Martínez.
http://www.sciencedirect.com/science/article/pii/S016819231730117X

Quinoa proteins (Chenopodium quinoa Willd.) fractionated by ultrafiltration using ceramic membranes: The role of pH on physicochemical and conformational properties.
Food and Bioproducts Processing, 102, 20-30.
Investigadores: Rosa Navarro-Lisboa, Camila Herrera, Rommy N. Zúñiga, Javier Enrione, Fanny Guzmán, Silvia Matiacevich y Carolina Astudillo-Castro.
http://www.sciencedirect.com/science/article/pii/S0960308516301560

Genome-scale metabolic reconstruction for the insidious bacterium in aquaculture Piscirickettsia salmonis.
Bioresource technology, 223, 105-114.
Investigadores: Pablo Fuentealba, Camila Aros, Yesenia Latorre, Irene Martínez, Sergio Marshall, Pau Ferrer, Joan Albiol y Claudia Altamirano.
http://www.sciencedirect.com/science/article/pii/S0960852416314304

Inverse method for the simultaneous estimation of the thermophysical properties of foods at freezing temperatures.
Journal of Food Engineering, 191, 37-47.
Investigadores: Iván Cornejo, Cornejo, G., Cristian Ramírez, Sergio Almonacid y Ricardo Simpson.
http://www.sciencedirect.com/science/article/pii/S0260877416302539

Phosphorus deficiency modifies as translocation in the halophyte plant species Atriplex atacamensis.
Ecotoxicology and Environmental Safety, 139, 344-351.
Investigadores: Delphine Vromman, Juan-Pablo Martínez, y Stanley Lutts.
http://www.sciencedirect.com/science/article/pii/S014765131730057X?via%3Dihub

Purification of galacto-oligosaccharides (GOS) by three-stage serial nanofiltration units under critical transmembrane pressure conditions.
Chemical Engineering Research and Design, 117, 488-499.
Investigadores: Andrés Córdova, Carolina Astudillo, Luciana Santibañez, Alfredo Cassano, René Ruby-Figueroa, y Andrés Illanes.
http://www.sciencedirect.com/science/article/pii/S0263876216304245?via%3Dihub

Industrial avocado waste: Functional compounds preservation by convective drying process.
Journal of Food Engineering, 198, 81-90.
Investigadores: Jorge Saavedra, Andrés Córdova, Rosa Navarro, Paulo Díaz-Calderón, Claudia Fuentealba, Carolina Astudillo-Castro, Lea Toledo, Javier Enrione y Lena Galvez.
http://www.sciencedirect.com/science/article/pii/S0260877416304332

Technical feasibility of glucose oxidase as a prefermentation treatment for lowering the alcoholic degree of red wine.
American Journal of Enology and Viticulture, 68(3), 386-389.
Investigadores: Pedro Valencia, Karen Espinoza, Cristian Ramirez, Wendy Franco y Alejandra Urtubia.
http://www.ajevonline.org/content/early/2017/03/15/ajev.2017.16005

Different responses in the expression of alginases, alginate polymerase and acetylation genes during alginate production by Azotobacter vinelandii under oxygen-controlled conditions.
Journal of Industrial Microbiology & Biotechnology, 1-11.
Investigadores: Alvaro Díaz-Barrera, Nataly Maturana, Ivette Pacheco-Leyva, Irene Martínez y Claudia Altamirano.
https://link.springer.com/article/10.1007%2Fs10295-017-1929-9

Effect of drum drying temperature on drying kinetic and polyphenol contents in pomegranate peel.
Journal of Food Engineering, 208, 19-27.
Investigadores: Galaz, P., Monika Valdenegro, Cristian Ramírez, Helena Nuñez, Sergio Almonacid y Ricardo Simpson.
http://www.sciencedirect.com/science/article/pii/S0260877417301425

Understanding the success of Page’s model and related empirical equations in fitting experimental data of diffusion phenomena in food matrices.
Trends in Food Science & Technology, 62, 194-201.
Investigadores: Ricardo Simpson, Cristian Ramírez, Helena Nuñez, Jaques, A. y Sergio Almonacid.
http://www.sciencedirect.com/science/article/pii/S0924224416304307

Production of combi-CLEAs of glycosidases utilized for aroma enhancement in wine.
Food and Bioproducts Processing, 94, 555-560.
Investigadores: Katherine Ahumada, Paulina Urrutia, Andrés Illanes y Lorena Wilson.
http://www.sciencedirect.com/science/article/pii/S0960308514000881#

Inhibition of enteropathogens adhesion to human enterocyte-like HT-29 cells by a dairy strain of Propionibacterium acidipropionici.
Beneficial microbes, 7(3), 431-441.
Investigadores: Zárate, G., Palacios, J. M., Villena, J. y María Elvira Zúñiga-Hansen.
http://www.ncbi.nlm.nih.gov/pubmed/26925604

Effect on rat blood pressure of epitaondiol, diterpenoid isolated from the algae stypopodium flabelliforme of rapanui (chilean island territory in the pacific ocean).
Investigadores: Martinez, J. L., Vinet, R., Laurido, C., Jaimes, L., Vargas-Rueda, S., Rovirosa, J. y San-Martin, A.
http://pharmacologyonline.silae.it/files/archives/2016/vol3/PhOL_2016_3_A030_48_Martinez.pdf

Purification of galacto-oligosaccharides (GOS) by three-stage serial nanofiltration units under critical transmembrane pressure conditions.
Chemical Engineering Research and Design, 117, 488-499.
Investigadores: Andrés Córdova, Carolina Astudillo, Luciana Santibañez, Alfredo Cassano, René Ruby-Figueroa y Andrés Illanes.
http://www.sciencedirect.com/science/article/pii/S0263876216304245

Industrial avocado waste: Functional compounds preservation by convective drying process.
Journal of Food Engineering, 198, 81-90.
Investigadores: Jorge Saavedra, Andrés Córdova, Rosa Navarro, Paulo Díaz-Calderón, Claudia Fuentealba, Carolina Astudillo-Castro, Lea Toledo, Javier Enrione y Lena Galvez.
https://www.sciencedirect.com/science/article/pii/S0260877416304332

Genome-scale metabolic reconstruction for the insidious bacterium in aquaculture Piscirickettsia salmonis.
Bioresource technology, 223, 105-114.
Investigadores: Pablo Fuentealba, Camila Aros, Yesenia Latorre, Irene Martínez, Sergio Marshall, Pau Ferrer, Joan Albiol y Claudia Altamirano.
https://www.sciencedirect.com/science/article/pii/S0960852416314304

Arsenic distribution in shoots of the halophyte plant species Atriplex atacamensis growing in an extreme arid mining area from northern Chile.
Journal of Bioremediation & Biodegradation, 7(349), 2.
Investigadores: Delphine Vromman, Bérengère Paternostre, Margarita Briceño, Carolina Teixeira-Cardoso, Alejandra Flores-Bavestrello, Nicolas Vanhecke, Mahendra Kumar, Juan-Pablo Martínez y Stanley Lutts.
https://doi.org/10.4172/2155-6199.1000349

Inhibition of ethylene synthesis reduces salt-tolerance in tomato wild relative species Solanum chilense.
Journal of plant physiology, 210, 24-37.
Investigadores: Emna Gharbiac, Juan-Pablo Martínez, Hela Benahmed, Gilles Lepoint, Brigitte Vanpee, Muriel Quinet y Stanley Lutts.
http://www.sciencedirect.com/science/article/pii/S0176161716302711

Inhibition of enteropathogens adhesion to human enterocyte-like HT-29 cells by a dairy strain of Propionibacterium acidipropionici.
Beneficial microbes, 7(3), 431-441.
Investigadores: Zárate, G., Palacios, J. M., Villena, J. y María Elvira Zúñiga-Hansen.
http://www.wageningenacademic.com/doi/10.3920/BM2015.0144

Methanisation of spent maqui berry pomace via enzymatic treatment.
Renewable Energy, 87, 326-331.
Investigadores: Alejandra Cerda, María Eugenia Martínez, Carmen Soto, María Elvira Zúñiga y Paola Poirrier.
https://www.sciencedirect.com/science/article/pii/S0960148115303803

The effects of drying processes on organoleptic characteristics and the health quality of food ingredients obtained from goldenberry fruits (Physalis peruviana).
Open Access Scientific Reports, 2(2), 1-7.
Investigadores: Valdenegro, M., Almonacid, S., Henríquez, C., Lutz, M., Fuentes, L., & Simpson, R. (2013).
https://www.omicsonline.org/scientific-reports/2157-7110-SR-642.pdf

Effect of isomalto-oligosaccharide and gentio-oligosaccharide on the growth and fatty acid profile of Lactobacillus plantarum.
Electronic Journal of Biotechnology, 16(4), 8-8.
Investigador: Carmen Soto
http://www.scielo.cl/pdf/ejb/v16n4/a08.pdf

Potential use of avocado oil on structured lipids MLM-type production catalysed by commercial immobilised lipases.
PloS one, 9(9), e107749.
Investigadores: Eduardo Caballero, Carmen Soto, Araceli Olivares, Claudia Altamirano.
http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0107749&type=printable

Production of pectic extracts from sugar beet pulp with antiproliferative activity on a breast cancer cell line.
Frontiers of Chemical Science and Engineering, 7(4), 482-489.
Investigadores: Jacqueline Concha, Caroline Weinstein y María Elvira Zúñiga.
https://link.springer.com/content/pdf/10.1007%2Fs11705-013-1342-5.pdf

A new mechanism and kinetic model for the enzymatic synthesis of short-chain fructooligosaccharides from sucrose.
Biochemical Engineering Journal, 82, 158-165.
Investigadores: Roberto Vega y María Elvira Zúñiga-Hansen.
https://www.sciencedirect.com/science/article/pii/S1369703X13003276

The enhancement of antioxidant compounds extracted from Thymus vulgaris using enzymes and the effect of extracting solvent.
Food chemistry, 139(1), 138-143.
Investigadores: Alejandra Cerda, María Eugenia Martínez, Carmen Soto, Paola Poirrier, José R. Perez-Correa, José R. Vergara-Salinas y María Elvira Zúñiga.
https://www.sciencedirect.com/science/article/pii/S0308814613000137

Effect of extraction conditions on total phenolic content and antioxidant capacity of pretreated wild Peumus boldus leaves from Chile.
Food and Bioproducts Processing, 92(3), 328-333.
Investigadores: Carmen Soto, Eduardo Caballero, Eduardo Pérez y María Elvira Zúñiga.
https://www.sciencedirect.com/science/article/pii/S0960308513000618

Identification of the key mechanisms involved in the hydrolysis of fish protein by Alcalase.
Process Biochemistry, 49(2), 258-264.
Investigadores: Pedro Valencia, Marlene Pinto y Sergio Almonacid.
https://www.sciencedirect.com/science/article/pii/S135951131300682X

Influence of ohmic heating/osmotic dehydration treatments on polyphenoloxidase inactivation, physical properties and microbial stability of apples (cv. Granny Smith).
Innovative Food Science & Emerging Technologies, 20, 198-207.
Investigadores: Moreno, J., Simpson, R., Pizarro, N., Pavez, C., Dorvil, F., Petzold, G. y Bugueño, G.
https://www.sciencedirect.com/science/article/pii/S1466856413000969

Production of alginate by Azotobacter vinelandii grown at two bioreactor scales under oxygen-limited conditions.
Bioprocess and biosystems engineering, 37(6), 1133-1140.
Investigadores: Alvaro Díaz-Barrera, Javiera Gutierrez, Fabiola Martínez, Claudia Altamirano.
https://link.springer.com/content/pdf/10.1007%2Fs00449-013-1084-2.pdf

Advances in improving mammalian cells metabolism for recombinant protein production.
Electronic Journal of Biotechnology, 16(3), 10-10.
Investigadores: Claudia Altamirano, Julio Berrios, Mauricio Vergara y Silvana Becerra.
http://www.ejbiotechnology.info/index.php/ejbiotechnology/article/view/v16n3-2/1601

Improving Amphetamine Therapeutic Selectivity: N, N‐dimethyl‐MTA has Dopaminergic Effects and does not Produce Aortic Contraction.
Basic & clinical pharmacology & toxicology, 114(5), 395-399.
Investigadores: Ramón Sotomayor-Zárate, Pablo Jara, Patricio Araos, Raúl Vinet, Gabriel Quiroz, Georgina M. Renard, Pedro Espinosa, Claudio Hurtado-Guzmán, Pablo R. Moya, Patricio Iturriaga-Vásquez, Katia Gysling y Miguel Reyes-Parada.
http://onlinelibrary.wiley.com/doi/10.1111/bcpt.12168/abstract

Differential effect of culture temperature and specific growth rate on CHO cell behavior in chemostat culture.
PloS one, 9(4), e93865.
Investigadores: Mauricio Vergara, Silvana Becerra, Julio Berrios, Nelson Osses, Juan Reyes, María Rodríguez-Moyá, Ramón González y Claudia Altamirano.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0093865#pone-0093865-g004

Effects of spray drying conditions and the addition of surfactants on the foaming properties of a whey protein concentrate.
LWT-Food Science and Technology, 58(1), 109-115.
Investigadores: Osorio, J., Monjes, J., Pinto, M., Ramírez, C., Simpson, R. y Vega, O.
https://www.sciencedirect.com/science/article/pii/S0023643814000929?via%3Dihub

Ohmic heating behaviour and electrical conductivity of two-phase food systems.
Innovative Food Science & Emerging Technologies, 4(1), 45-55.
Investigadores: Zareifard, M. R., Ramaswamy, H. S., Trigui, M. y Marcotte, M.
https://www.sciencedirect.com/science/article/pii/S1466856402000887

The effect of processing conditions on the stability of fructooligosaccharides in acidic food products.
Food chemistry, 173, 784-789.
Investigadores: Roberto Vega y María Elvira Zúñiga-Hansen
http://www.sciencedirect.com/science/article/pii/S0308814614016835?via%3Dihub

Characterization of pressurized hot water extracts of grape pomace: chemical and biological antioxidant activity.
Food chemistry, 171, 62-69.
Investigadores: J.R. Vergara-Salinas, Mauricio Vergara, Claudia Altamirano, Álvaro González y J.R. Pérez-Correa
https://www.sciencedirect.com/science/article/pii/S0308814614013193

P-Coumaric acid reduces high glucose-mediated impairment of endothelium-dependent relaxation in rat aorta.
Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas, 13(3).
Investigadores: Raúl Vinet, Patricio Araos, Juan Carlos Gentina, Marcela Knox y Leda Guzmán
http://www.redalyc.org/articulo.oa?id=85631010002

Bradykinin and histamine‐induced cytosolic calcium increase in capillary endothelial cells of bovine adrenal medulla.
Cell biology international, 38(9), 1023-1031.
Investigadores: Raúl Vinet, Magdalena P. Cortés, Rocío Álvarez y Marco Delpiano
https://onlinelibrary.wiley.com/doi/epdf/10.1002/cbin.10300

Shellfish (Mussel) processing and components.
In Processing and impact on active components in food (pp. 447-454).
Investigadores: Sergio Almonacid, Joselyn Bustamante, Ricardo Simpson y Marlene Pinto
https://www.researchgate.net/publication/283382629_Shellfish_Mussel_Processing_and_Components

Effect of extraction conditions on total phenolic content and antioxidant capacity of pretreated wild Peumus boldus leaves from Chile.
Food and Bioproducts Processing, 92(3), 328-333.
Investigadores: Carmen Soto, Eduardo Caballero, Eduardo Pérez y María Elvira Zúñiga
https://www.sciencedirect.com/science/article/pii/S0960308513000618

Potential use of avocado oil on structured lipids MLM-type production catalysed by commercial immobilised lipases.
PloS one, 9(9), e107749.
Investigadores: Eduardo Caballero, Carmen Soto, Araceli Olivares y Claudia Altamirano
http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0107749&type=printable

Differential expression of ethylene biosynthesis genes in drupelets and receptacle of raspberry (Rubus idaeus).
Journal of plant physiology, 179, 100-105.
Investigadores: Lida Fuentes, Liliam Monsalve, Luis Morales-Quintana, Mónika Valdenegro, Juan-Pablo Martínez, Bruno G. Defilippi y Mauricio González-Agüero
https://www.sciencedirect.com/science/article/pii/S0176161715000437

Study of effect of sodium alginate on potato starch digestibility during in vitro digestion.
Food Hydrocolloids, 44, 328-332.
Investigadores: Cristian Ramírez, Camila Millon, Helena Nuñez, Marlene Pinto, Pedro Valencia, Cristian Acevedo y Ricardo Simpson
https://www.sciencedirect.com/science/article/pii/S0268005X14003440

Novel modeling methodology for the characterization of enzymatic hydrolysis of proteins.
Process Biochemistry, 50(4), 589-597.
Investigadores: Pedro Valencia, Karen Espinoza, Andrés Ceballos, Marlene Pinto y Sergio Almonacid
https://www.sciencedirect.com/science/article/pii/S1359511315000148

Effect of soil available water depletion on plant water status, fruit size and yield of avocado trees cv.’HASS’.
In VII International Symposium on Irrigation of Horticultural Crops 1038 (pp. 393-400).
Investigadores: Ferreyra, R., Selles, G., Gil, P., Celedon, J. y Maldonado, P.
http://www.actahort.org/books/1038/1038_47.htm

Characterization of pressurized hot water extracts of grape pomace: chemical and biological antioxidant activity.
Food chemistry, 171, 62-69.
Investigadores: J.R. Vergara-Salinas, Mauricio Vergara, Claudia Altamirano, Álvaro González y J.R. Pérez-Correa.
https://www.sciencedirect.com/science/article/pii/S0308814614013193

Assessment of antiproliferative activity of pectic substances obtained by different extraction methods from rapeseed cake on cancer cell lines.
Carbohydrate polymers, 117, 923-932.
Investigadores: M. Cobs-Rosas, J. Concha-Olmos, C. Weinstein-Oppenheimer y María Elvira Zúñiga-Hansen
https://www.sciencedirect.com/science/article/pii/S0144861714010327